“`html<\/p>\n
Khoang mi\u1ec7ng l\u00e0 n\u01a1i c\u01b0 tr\u00fa c\u1ee7a m\u1ed9t c\u1ed9ng \u0111\u1ed3ng vi sinh v\u1eadt ph\u1ee9c t\u1ea1p, \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c b\u1ea3o v\u1ec7 c\u00e1c m\u00f4, duy tr\u00ec t\u00ednh to\u00e0n v\u1eb9n c\u1ee7a ni\u00eam m\u1ea1c v\u00e0 \u0111i\u1ec1u ch\u1ec9nh c\u00e1c ph\u1ea3n \u1ee9ng vi\u00eam. H\u1ec7 vi sinh v\u1eadt n\u00e0y, \u0111\u1ee9ng th\u1ee9 hai v\u1ec1 quy m\u00f4 trong c\u01a1 th\u1ec3 sau h\u1ec7 vi sinh v\u1eadt \u0111\u01b0\u1eddng ru\u1ed9t, c\u0169ng tham gia v\u00e0o vi\u1ec7c c\u00e2n b\u1eb1ng h\u1ec7 mi\u1ec5n d\u1ecbch, c\u1ea3 \u1edf c\u1ea5p \u0111\u1ed9 \u0111\u1ecba ph\u01b0\u01a1ng l\u1eabn to\u00e0n th\u00e2n. Tuy nhi\u00ean, s\u1ef1 m\u1ea5t c\u00e2n b\u1eb1ng c\u1ee7a h\u1ec7 vi sinh v\u1eadt n\u00e0y, \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 lo\u1ea1n khu\u1ea9n, ng\u00e0y c\u00e0ng \u0111\u01b0\u1ee3c li\u00ean k\u1ebft v\u1edbi s\u1ef1 xu\u1ea5t hi\u1ec7n v\u00e0 ti\u1ebfn tri\u1ec3n c\u1ee7a nhi\u1ec1u lo\u1ea1i ung th\u01b0, cho d\u00f9 ch\u00fang n\u1eb1m trong khoang mi\u1ec7ng hay \u1edf c\u00e1c b\u1ed9 ph\u1eadn kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3 nh\u01b0 \u0111\u1ea1i tr\u00e0ng, gan hay tuy\u1ebfn t\u1ee5y.<\/p>\n
M\u1ed9t s\u1ed1 vi khu\u1ea9n g\u00e2y b\u1ec7nh, ch\u1eb3ng h\u1ea1n nh\u01b0 Porphyromonas gingivalis<\/em> v\u00e0 Fusobacterium nucleatum<\/em>, \u0111\u1eb7c bi\u1ec7t tham gia v\u00e0o c\u00e1c qu\u00e1 tr\u00ecnh n\u00e0y. Ch\u00fang th\u00fac \u0111\u1ea9y s\u1ef1 h\u00ecnh th\u00e0nh kh\u1ed1i u b\u1eb1ng c\u00e1ch thay \u0111\u1ed5i m\u00f4i tr\u01b0\u1eddng vi\u00eam, l\u00e0m m\u1ea5t \u1ed5n \u0111\u1ecbnh ADN c\u1ee7a c\u00e1c t\u1ebf b\u00e0o ch\u1ee7 ho\u1eb7c k\u00edch th\u00edch s\u1ef1 h\u00ecnh th\u00e0nh c\u00e1c m\u1ea1ch m\u00e1u m\u1edbi xung quanh kh\u1ed1i u. Nh\u1eefng vi sinh v\u1eadt n\u00e0y c\u00f2n c\u00f3 th\u1ec3 di chuy\u1ec3n t\u1eeb mi\u1ec7ng \u0111\u1ebfn c\u00e1c v\u00f9ng kh\u00e1c c\u1ee7a c\u01a1 th\u1ec3, ch\u1eb3ng h\u1ea1n nh\u01b0 \u1ed1ng ti\u00eau h\u00f3a, n\u01a1i ch\u00fang l\u00e0m suy y\u1ebfu h\u1ec7 th\u1ed1ng ph\u00f2ng th\u1ee7 \u0111\u1ecba ph\u01b0\u01a1ng v\u00e0 t\u1ea1o ra m\u00f4i tr\u01b0\u1eddng thu\u1eadn l\u1ee3i cho s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a ung th\u01b0. V\u00ed d\u1ee5, Fusobacterium nucleatum<\/em> th\u01b0\u1eddng \u0111\u01b0\u1ee3c t\u00ecm th\u1ea5y v\u1edbi s\u1ed1 l\u01b0\u1ee3ng l\u1edbn trong c\u00e1c m\u00f4 ung th\u01b0 c\u1ee7a \u0111\u1ea1i tr\u00e0ng, gan ho\u1eb7c th\u1ef1c qu\u1ea3n, trong khi n\u1ed3ng \u0111\u1ed9 cao c\u1ee7a Porphyromonas gingivalis<\/em> \u0111\u01b0\u1ee3c ph\u00e1t hi\u1ec7n trong n\u01b0\u1edbc b\u1ecdt c\u1ee7a b\u1ec7nh nh\u00e2n m\u1eafc c\u00e1c lo\u1ea1i ung th\u01b0 n\u00e0y.<\/p>\n S\u1ef1 lo\u1ea1n khu\u1ea9n trong mi\u1ec7ng kh\u00f4ng ch\u1ec9 \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 kh\u1edfi ph\u00e1t c\u1ee7a kh\u1ed1i u m\u00e0 c\u00f2n \u0111\u00f3ng vai tr\u00f2 trong s\u1ef1 ti\u1ebfn tri\u1ec3n v\u00e0 ti\u00ean l\u01b0\u1ee3ng c\u1ee7a ch\u00fang. \u1ede b\u1ec7nh nh\u00e2n ung th\u01b0, th\u00e0nh ph\u1ea7n c\u1ee7a h\u1ec7 vi sinh v\u1eadt mi\u1ec7ng th\u01b0\u1eddng b\u1ecb thay \u0111\u1ed5i, v\u1edbi s\u1ef1 gi\u1ea3m s\u00fat v\u1ec1 \u0111a d\u1ea1ng vi sinh v\u1eadt v\u00e0 s\u1ef1 bi\u1ebfn \u0111\u1ed5i v\u1ec1 s\u1ed1 l\u01b0\u1ee3ng c\u1ee7a m\u1ed9t s\u1ed1 lo\u00e0i. Nh\u1eefng thay \u0111\u1ed5i n\u00e0y c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam t\u00ecnh tr\u1ea1ng vi\u00eam m\u1ea1n t\u00ednh, suy y\u1ebfu h\u1ec7 mi\u1ec5n d\u1ecbch ho\u1eb7c th\u00fac \u0111\u1ea9y kh\u1ea3 n\u0103ng kh\u00e1ng tr\u1ecb. Ch\u1eb3ng h\u1ea1n, s\u1ef1 \u0111a d\u1ea1ng vi sinh v\u1eadt th\u1ea5p trong n\u01b0\u1edbc b\u1ecdt li\u00ean quan \u0111\u1ebfn t\u1ef7 l\u1ec7 t\u1eed vong cao h\u01a1n \u1edf nh\u1eefng ng\u01b0\u1eddi m\u1eafc ung th\u01b0 v\u00f2m h\u1ecdng, trong khi s\u1ef1 phong ph\u00fa vi sinh v\u1eadt l\u1edbn h\u01a1n trong c\u00e1c m\u00f4 kh\u1ecfe m\u1ea1nh c\u1ee7a b\u1ec7nh nh\u00e2n ung th\u01b0 ph\u1ed5i \u0111\u01b0\u1ee3c li\u00ean k\u1ebft v\u1edbi nguy c\u01a1 t\u00e1i ph\u00e1t th\u1ea5p h\u01a1n v\u00e0 th\u1eddi gian s\u1ed1ng l\u00e2u h\u01a1n.<\/p>\n H\u1ec7 vi sinh v\u1eadt mi\u1ec7ng c\u00f2n c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng nh\u01b0 m\u1ed9t c\u00f4ng c\u1ee5 ph\u00e1t hi\u1ec7n s\u1edbm. C\u00e1c nghi\u00ean c\u1ee9u cho th\u1ea5y vi\u1ec7c ph\u00e2n t\u00edch n\u01b0\u1edbc b\u1ecdt cho ph\u00e9p ph\u00e2n bi\u1ec7t b\u1ec7nh nh\u00e2n ung th\u01b0 mi\u1ec7ng v\u1edbi ng\u01b0\u1eddi kh\u1ecfe m\u1ea1nh v\u1edbi \u0111\u1ed9 ch\u00ednh x\u00e1c v\u01b0\u1ee3t qu\u00e1 90%. T\u01b0\u01a1ng t\u1ef1, h\u1ec7 vi sinh v\u1eadt trong n\u01b0\u1edbc b\u1ecdt c\u0169ng c\u00f3 kh\u1ea3 n\u0103ng d\u1ef1 \u0111o\u00e1n t\u1ed1t cho vi\u1ec7c s\u00e0ng l\u1ecdc ung th\u01b0 d\u1ea1 d\u00e0y, v\u1edbi hi\u1ec7u su\u1ea5t t\u01b0\u01a1ng \u0111\u01b0\u01a1ng, th\u1eadm ch\u00ed v\u01b0\u1ee3t tr\u1ed9i so v\u1edbi c\u00e1c x\u00e9t nghi\u1ec7m truy\u1ec1n th\u1ed1ng. M\u1ed9t ph\u01b0\u01a1ng ph\u00e1p k\u1ebft h\u1ee3p ph\u00e2n t\u00edch h\u1ec7 vi sinh v\u1eadt mi\u1ec7ng v\u00e0 ph\u00e2n c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n vi\u1ec7c ph\u00e1t hi\u1ec7n ung th\u01b0 \u0111\u1ea1i tr\u1ef1c tr\u00e0ng, v\u1edbi \u0111\u1ed9 \u0111\u1eb7c hi\u1ec7u 95% v\u00e0 \u0111\u1ed9 nh\u1ea1y 88%.<\/p>\n C\u01a1 ch\u1ebf m\u00e0 h\u1ec7 vi sinh v\u1eadt mi\u1ec7ng \u0111\u00f3ng g\u00f3p v\u00e0o qu\u00e1 tr\u00ecnh g\u00e2y ung th\u01b0 l\u00e0 \u0111a d\u1ea1ng. T\u00ecnh tr\u1ea1ng vi\u00eam m\u1ea1n t\u00ednh, do m\u1ea5t c\u00e2n b\u1eb1ng vi sinh v\u1eadt g\u00e2y ra, t\u1ea1o ra m\u00f4i tr\u01b0\u1eddng thu\u1eadn l\u1ee3i cho s\u1ef1 t\u0103ng sinh t\u1ebf b\u00e0o, \u0111\u1ed9t bi\u1ebfn gen v\u00e0 k\u00edch ho\u1ea1t c\u00e1c gen li\u00ean quan \u0111\u1ebfn s\u1ef1 h\u00ecnh th\u00e0nh kh\u1ed1i u. M\u1ed9t s\u1ed1 vi sinh v\u1eadt c\u00f2n s\u1ea3n xu\u1ea5t c\u00e1c ch\u1ea5t g\u00e2y ung th\u01b0, ch\u1eb3ng h\u1ea1n nh\u01b0 acetaldehyde, sinh ra t\u1eeb qu\u00e1 tr\u00ecnh chuy\u1ec3n h\u00f3a ethanol, g\u00e2y t\u1ed5n th\u01b0\u01a1ng ADN v\u00e0 th\u00fac \u0111\u1ea9y s\u1ef1 bi\u1ebfn \u0111\u1ed5i \u00e1c t\u00ednh c\u1ee7a t\u1ebf b\u00e0o. Ngo\u00e0i ra, vi khu\u1ea9n mi\u1ec7ng c\u00f3 th\u1ec3 t\u01b0\u01a1ng t\u00e1c v\u1edbi h\u1ec7 mi\u1ec5n d\u1ecbch c\u1ee7a v\u1eadt ch\u1ee7, b\u1eb1ng c\u00e1ch k\u00edch ho\u1ea1t c\u00e1c con \u0111\u01b0\u1eddng t\u00edn hi\u1ec7u l\u00e0m suy y\u1ebfu ph\u1ea3n \u1ee9ng ch\u1ed1ng kh\u1ed1i u ho\u1eb7c tuy\u1ec3n d\u1ee5ng c\u00e1c t\u1ebf b\u00e0o mi\u1ec5n d\u1ecbch \u1ee9c ch\u1ebf, ch\u1eb3ng h\u1ea1n nh\u01b0 t\u1ebf b\u00e0o T \u0111i\u1ec1u h\u00f2a, b\u1ea3o v\u1ec7 kh\u1ed1i u kh\u1ecfi s\u1ef1 t\u1ea5n c\u00f4ng c\u1ee7a h\u1ec7 mi\u1ec5n d\u1ecbch.<\/p>\n C\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0, ch\u1eb3ng h\u1ea1n nh\u01b0 h\u00f3a tr\u1ecb ho\u1eb7c x\u1ea1 tr\u1ecb, c\u0169ng l\u00e0m gi\u00e1n \u0111o\u1ea1n s\u1ef1 c\u00e2n b\u1eb1ng c\u1ee7a h\u1ec7 vi sinh v\u1eadt mi\u1ec7ng. Ch\u00fang th\u01b0\u1eddng g\u00e2y ra vi\u00eam ni\u00eam m\u1ea1c mi\u1ec7ng, m\u1ed9t t\u00ecnh tr\u1ea1ng vi\u00eam ni\u00eam m\u1ea1c mi\u1ec7ng l\u00e0m thay \u0111\u1ed5i th\u00e0nh ph\u1ea7n vi sinh v\u1eadt v\u00e0 th\u00fac \u0111\u1ea9y c\u00e1c nhi\u1ec5m tr\u00f9ng c\u01a1 h\u1ed9i. Nh\u1eefng thay \u0111\u1ed5i n\u00e0y c\u00f3 th\u1ec3 l\u00e0m tr\u1ea7m tr\u1ecdng th\u00eam c\u00e1c bi\u1ebfn ch\u1ee9ng \u0111\u1ecba ph\u01b0\u01a1ng v\u00e0 to\u00e0n th\u00e2n, ch\u1eb3ng h\u1ea1n nh\u01b0 s\u1ef1 l\u00e2y lan c\u1ee7a nhi\u1ec5m tr\u00f9ng ho\u1eb7c t\u00ecnh tr\u1ea1ng \u1ee9c ch\u1ebf mi\u1ec5n d\u1ecbch nghi\u00eam tr\u1ecdng, \u0111i\u1ec1u n\u00e0y c\u00f3 th\u1ec3 \u0111e d\u1ecda hi\u1ec7u qu\u1ea3 c\u1ee7a \u0111i\u1ec1u tr\u1ecb v\u00e0 s\u1ef1 s\u1ed1ng s\u00f3t c\u1ee7a b\u1ec7nh nh\u00e2n.<\/p>\n Cu\u1ed1i c\u00f9ng, h\u1ec7 vi sinh v\u1eadt mi\u1ec7ng c\u00f3 th\u1ec3 tr\u1edf th\u00e0nh m\u1ed9t m\u1ee5c ti\u00eau \u0111i\u1ec1u tr\u1ecb \u0111\u1ea7y h\u1ee9a h\u1eb9n. C\u00e1c ph\u01b0\u01a1ng ph\u00e1p nh\u1eb1m \u0111i\u1ec1u ch\u1ec9nh h\u1ec7 vi sinh v\u1eadt n\u00e0y, ch\u1eb3ng h\u1ea1n nh\u01b0 s\u1eed d\u1ee5ng men vi sinh ho\u1eb7c kh\u00e1ng sinh nh\u1eafm m\u1ee5c ti\u00eau, c\u00f3 th\u1ec3 gi\u00fap kh\u00f4i ph\u1ee5c s\u1ef1 c\u00e2n b\u1eb1ng c\u00f3 l\u1ee3i cho cu\u1ed9c chi\u1ebfn ch\u1ed1ng ung th\u01b0. M\u1eb7c d\u00f9 c\u00e1c b\u1eb1ng ch\u1ee9ng l\u00e2m s\u00e0ng v\u1eabn c\u00f2n h\u1ea1n ch\u1ebf, nh\u01b0ng c\u00e1c nghi\u00ean c\u1ee9u ban \u0111\u1ea7u cho th\u1ea5y nh\u1eefng can thi\u1ec7p n\u00e0y c\u00f3 th\u1ec3 c\u1ea3i thi\u1ec7n ph\u1ea3n \u1ee9ng v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb ung th\u01b0 b\u1eb1ng c\u00e1ch \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn c\u00e1c con \u0111\u01b0\u1eddng vi\u00eam v\u00e0 mi\u1ec5n d\u1ecbch. Trong t\u01b0\u01a1ng lai, vi\u1ec7c hi\u1ec3u r\u00f5 h\u01a1n v\u1ec1 s\u1ef1 t\u01b0\u01a1ng t\u00e1c gi\u1eefa h\u1ec7 vi sinh v\u1eadt mi\u1ec7ng v\u00e0 kh\u1ed1i u c\u00f3 th\u1ec3 m\u1edf ra con \u0111\u01b0\u1eddng cho c\u00e1c chi\u1ebfn l\u01b0\u1ee3c m\u1edbi v\u1ec1 ph\u00f2ng ng\u1eeba, ph\u00e1t hi\u1ec7n s\u1edbm v\u00e0 \u0111i\u1ec1u tr\u1ecb c\u00e1 nh\u00e2n h\u00f3a.<\/p>\n “`<\/p>\n DOI\u00a0:<\/strong> https:\/\/doi.org\/10.1007\/s44178-026-00270-z<\/a><\/p>\n Titre\u00a0:<\/strong> Research advances in the correlation between oral microbiota and tumors<\/p>\n Revue : <\/strong> Holistic Integrative Oncology<\/p>\n \u00c9diteur : <\/strong> Springer Science and Business Media LLC<\/p>\n Auteurs : <\/strong> Xiaoxuan Liu; Shan Liu; Zhi Guo<\/p>\n","protected":false},"excerpt":{"rendered":" “`html Vi sinh v\u1eadt mi\u1ec7ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a kh\u1ed1i u Khoang mi\u1ec7ng l\u00e0 n\u01a1i c\u01b0 tr\u00fa c\u1ee7a m\u1ed9t c\u1ed9ng \u0111\u1ed3ng vi sinh v\u1eadt ph\u1ee9c t\u1ea1p, \u0111\u00f3ng vai tr\u00f2 quan tr\u1ecdng trong vi\u1ec7c b\u1ea3o v\u1ec7 c\u00e1c m\u00f4, duy tr\u00ec t\u00ednh to\u00e0n v\u1eb9n c\u1ee7a ni\u00eam m\u1ea1c v\u00e0 \u0111i\u1ec1u ch\u1ec9nh c\u00e1c ph\u1ea3n \u1ee9ng vi\u00eam.… Continue reading Vi sinh v\u1eadt mi\u1ec7ng \u1ea3nh h\u01b0\u1edfng \u0111\u1ebfn s\u1ef1 ph\u00e1t tri\u1ec3n c\u1ee7a kh\u1ed1i u<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[3,2,4],"tags":[],"class_list":["post-17","post","type-post","status-publish","format-standard","hentry","category-moi-truong","category-suc-khoe","category-xa-hoi","entry"],"_links":{"self":[{"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/posts\/17","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/comments?post=17"}],"version-history":[{"count":1,"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/posts\/17\/revisions"}],"predecessor-version":[{"id":18,"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/posts\/17\/revisions\/18"}],"wp:attachment":[{"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/media?parent=17"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/categories?post=17"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/themedicinereview.com\/vi\/wp-json\/wp\/v2\/tags?post=17"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nAttributions l\u00e9gales<\/h2>\n
Citation de l\u2019\u00e9tude<\/h3>\n